Pathobiology of Left Ventricular Dyssynchrony and Resynchronization

Robert H. Helm, David D. Spragg, Khalid Chakir, David A. Kass

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
Original languageEnglish (US)
Title of host publicationPacing to Support the Failing Heart
Number of pages26
ISBN (Print)9781405175340
StatePublished - Feb 26 2009


  • Acute effects from cardiac resynchronization therapy
  • Altered gene expression
  • CRT reverses localized molecular remodeling and enhances global cell-survival signaling
  • Dyssynchrony, relaxation, and loading
  • Effect of dyssynchrony on global function and efficiency
  • Electrophysiologic alterations and arrhythmia susceptibility
  • Heart failure and resynchronization therapy
  • Mechanics of dyssynchrony
  • Pathobiology of left ventricular dyssynchrony

ASJC Scopus subject areas

  • Medicine(all)

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