Participant retention in follow-up studies of acute respiratory failure survivors

Krishidhar Nunna, Awsse Al-Ani, Roozbeh Nikooie, Lisa Aronson Friedman, Vaishnavi Raman, Zerka Wadood, Sumana Vasishta, Elizabeth Colantuoni, Dale M. Needham, Victor D. Dinglas

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


BACKGROUND: With an increasing number of follow-up studies of acute respiratory failure survivors, there is need for a better understanding of participant retention and its reporting in this field of research. Hence, our objective was to synthesize participant retention data and associated reporting for this field. METHODS: Two screeners independently searched for acute respiratory failure survivorship studies within a published scoping review to evaluate subject outcomes after hospital discharge in critical illness survivors. RESULTS: There were 21 acute respiratory failure studies (n = 4,342 survivors) over 47 follow-up time points. Six-month fol-low-up (range: 2–60 months) was the most frequently reported time point, in 81% of studies. Only 1 study (5%) reported accounting for loss to follow-up in sample-size calculation. Retention rates could not be calculated for 5 (24%) studies. In 16 studies reporting on retention across all time points, retention ranged from 32% to 100%. Pooled retention rates at 3, 6, 12, and 24 months were 85%, 89%, 82%, and 88%, respectively. Retention rates did not significantly differ by publication year, participant mean age, or when comparing earlier (3 months) versus each later follow-up time point (6, 12, or 24 months). CONCLUSIONS: Participant retention was generally high but varied greatly across individual studies and time points, with 24% of studies reporting inadequate data to calculate retention rate. High participant retention is possi-ble, but resources for optimizing retention may help studies retain participants. Improved reporting guidelines with greater adherence would be beneficial.

Original languageEnglish (US)
Pages (from-to)1382-1391
Number of pages10
JournalRespiratory care
Issue number9
StatePublished - Sep 1 2020


  • Acute respiratory failure
  • Cohort
  • Follow-up studies. [Respir Care
  • Meta-analysis
  • Participant retention
  • Systematic review

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


Dive into the research topics of 'Participant retention in follow-up studies of acute respiratory failure survivors'. Together they form a unique fingerprint.

Cite this