Parotid Swelling During Human Immunodeficiency Virus Infection

Robert Colebunders, Henry Francis, Jonathan M. Mann, Kapita M. Bila, Kandi Kandi, Izaley Lebughe, Paul Gigase, Erik Van Marck, Abe M. Macher, Thomas C. Quinn, James W. Curran, Peter Piot

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29 Scopus citations


• In Europe and in the United States, bilateral parotid gland swelling has been observed as a sign of human immunodeficiency virus (HIV) infection in children, but it has not been associated with HIV infection in adults. We observed a chronic parotid gland swelling in nine HIV-seropositive patients during a nine-month period in Kinshasa, Zaire. Parotid gland enlargement was bilateral in seven patients (78%), slightly painful in seven patients (78%), and painless in two patients (22%). No evidence of inflammation was observed around Stensen's duct. One of the two patients in whom a parotid gland biopsy was performed had a malignant lymphoma of the large-cell, histiocytic type. In the other patient, the parotid gland showed normal morphology with minor inflammation. Among 284 adults and 40 children with symptomatic HIV infection, chronic parotid gland enlargement was observed in none of the patients. However, two (0.7%) of the adults presented with an acute pyogenic parotitis. Further studies are needed to determine whether parotid gland enlargement is associated with HIV infection. (Arch Otolaryngol Head Neck Surg 1988;114:330-332).

Original languageEnglish (US)
Pages (from-to)330-332
Number of pages3
JournalArchives of Otolaryngology--Head and Neck Surgery
Issue number3
StatePublished - Mar 1988
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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