Panorama of DNA hairpin folding observed via diffusion-decelerated fluorescence correlation spectroscopy

Yandong Yin; Peng Wang; Xin Xing Yang; Xun Li; Chuan He; Xin Sheng Zhao

doi:10.1039/c2cc31986a

Panorama of DNA hairpin folding observed via diffusion-decelerated fluorescence correlation spectroscopy

Yandong Yin, Peng Wang, Xin Xing Yang, Xun Li, Chuan He, Xin Sheng Zhao

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Based on a confocal microscopy platform, we extended the FCS time window by three orders of magnitude to the s timescale by attaching a polystyrene microsphere. We simultaneously monitored the relaxations of multiple intermediates involved in DNA hairpin folding, thus offering a much more detailed view of the kinetics of hairpin folding experimentally.

Original language	English (US)
Pages (from-to)	7413-7415
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	59
DOIs	https://doi.org/10.1039/c2cc31986a
State	Published - Jun 27 2012
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
General Chemistry
Catalysis

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10.1039/c2cc31986a

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title = "Panorama of DNA hairpin folding observed via diffusion-decelerated fluorescence correlation spectroscopy",

abstract = "Based on a confocal microscopy platform, we extended the FCS time window by three orders of magnitude to the s timescale by attaching a polystyrene microsphere. We simultaneously monitored the relaxations of multiple intermediates involved in DNA hairpin folding, thus offering a much more detailed view of the kinetics of hairpin folding experimentally.",

author = "Yandong Yin and Peng Wang and Yang, {Xin Xing} and Xun Li and Chuan He and Zhao, {Xin Sheng}",

year = "2012",

month = jun,

day = "27",

doi = "10.1039/c2cc31986a",

language = "English (US)",

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T1 - Panorama of DNA hairpin folding observed via diffusion-decelerated fluorescence correlation spectroscopy

AU - Yin, Yandong

AU - Wang, Peng

AU - Yang, Xin Xing

AU - Li, Xun

AU - He, Chuan

AU - Zhao, Xin Sheng

PY - 2012/6/27

Y1 - 2012/6/27

N2 - Based on a confocal microscopy platform, we extended the FCS time window by three orders of magnitude to the s timescale by attaching a polystyrene microsphere. We simultaneously monitored the relaxations of multiple intermediates involved in DNA hairpin folding, thus offering a much more detailed view of the kinetics of hairpin folding experimentally.

AB - Based on a confocal microscopy platform, we extended the FCS time window by three orders of magnitude to the s timescale by attaching a polystyrene microsphere. We simultaneously monitored the relaxations of multiple intermediates involved in DNA hairpin folding, thus offering a much more detailed view of the kinetics of hairpin folding experimentally.

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U2 - 10.1039/c2cc31986a

DO - 10.1039/c2cc31986a

M3 - Article

C2 - 22715462

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VL - 48

SP - 7413

EP - 7415

JO - Chemical Communications

JF - Chemical Communications

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ER -

Panorama of DNA hairpin folding observed via diffusion-decelerated fluorescence correlation spectroscopy

Abstract

ASJC Scopus subject areas

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