PANDAS

D. S. Wolf; H. S. Singer

doi:10.1016/B978-0-12-374105-9.00059-9

PANDAS

D. S. Wolf, H. S. Singer

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

PANDAS is the acronym for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection. It requires an abrupt onset and repeat exacerbations of tics/obsessive-compulsive behaviors occurring in temporal association with a Group A β-hemolytic streptococcal infection (GABHS). Since its initial description, investigators have been actively seeking to confirm diagnostic criteria, validate the temporal association of GABHS, document abnormalities of immune markers, and establish an association between infection-related clinical exacerbation and alterations in the level of antineuronal antibodies or cytokines. Clinical and scientific investigations are useful to support or refute the diagnosis of PANDAS.

Original language	English (US)
Title of host publication	Encyclopedia of Movement Disorders
Publisher	Elsevier Inc.
Pages	369-373
Number of pages	5
ISBN (Electronic)	9780123741059
ISBN (Print)	9780123741011
DOIs	https://doi.org/10.1016/B978-0-12-374105-9.00059-9
State	Published - Jan 1 2010

Keywords

Antineuronal antibodies
Cytokines
Group A β-hemolytic streptococcal infection
OCD
PANDAS
Sydenham chorea
Tics
Tourette syndrome

ASJC Scopus subject areas

General Medicine
General Neuroscience

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10.1016/B978-0-12-374105-9.00059-9

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abstract = "PANDAS is the acronym for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection. It requires an abrupt onset and repeat exacerbations of tics/obsessive-compulsive behaviors occurring in temporal association with a Group A β-hemolytic streptococcal infection (GABHS). Since its initial description, investigators have been actively seeking to confirm diagnostic criteria, validate the temporal association of GABHS, document abnormalities of immune markers, and establish an association between infection-related clinical exacerbation and alterations in the level of antineuronal antibodies or cytokines. Clinical and scientific investigations are useful to support or refute the diagnosis of PANDAS.",

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KW - OCD

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KW - Sydenham chorea

KW - Tics

KW - Tourette syndrome

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PANDAS

Abstract

Keywords

ASJC Scopus subject areas

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