Pain and obesity in the older adult

Robert Taylor, Joseph V. Pergolizzi, Robert B. Raffa, Srinivas Nalamachu, Philip J. Balestrieri

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Obesity and pain are common problems affecting the older adult and a possible relationship between the two is considered. Obesity and pain themselves are significant burdens on the individual, the healthcare system, and society as a whole and they can lead to emotional conditions such as stress, anxiety, and depression – which lead to further healthcare utilization and burden. Cross-sectional studies have revealed a high correlation between pain and obesity and a few longitudinal studies implicate obesity as a risk factor for the development of pain and the associated reduction in quality of life. Obesity leads to pain due to mechanical stress and metabolic disruptions, so mitigating obesity may help reduce the risk of developing pain and improve recovery from pain. More research is warranted to elucidate the mechanistic links between obesity and pain and to determine the optimal treatment strategies for reducing these comorbities. Reducing obesity could reduce pain medication burden.

Original languageEnglish (US)
Pages (from-to)6037-6041
Number of pages5
JournalCurrent Pharmaceutical Design
Issue number38
StatePublished - Jan 1 2014


  • Chronic pain
  • Fibromyalgia
  • Inflammation
  • Obesity
  • Osteoarthritis
  • Quality of life

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology
  • Medicine(all)


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