P62/SQSTM1 accumulation in squamous cell carcinoma of head and neck predicts sensitivity to phosphatidylinositol 3-Kinase pathway inhibitors

Agriculture & Biology

• squamous cell carcinoma 83%
• phosphatidylinositol 3-kinase 78%
• autophagy 71%
• neck 57%
• phosphotransferases (kinases) 39%
• neoplasms 15%
• epigenetics 6%
• data analysis 6%
• tissues 5%
• homeostasis 5%
• cell lines 4%
• sampling 4%
• genes 4%
• mutation 4%
• proteins 4%
• drugs 4%

Medicine & Life Sciences

• Squamous Cell Carcinoma of Head and Neck 66%
• Phosphatidylinositol 3-Kinase 60%
• Autophagy 57%
• Phosphotransferases 46%
• Macroautophagy 11%
• Essential Genes 9%
• Neoplasms 8%
• Epigenomics 7%
• Data Analysis 6%
• Homeostasis 6%
• Down-Regulation 6%
• Cell Line 5%
• Messenger RNA 4%
• Mutation 4%
• Survival 4%
• Pharmaceutical Preparations 3%
• Genes 3%
• Proteins 3%

Chemical Compounds

• Pathway Inhibitor 99%
• Phosphatidylinositol 72%
• Catabolic 15%
• Resistance 15%
• Marker 10%
• Mutation 10%
• Protein 9%
• Modification 6%
• Drug 6%