Overlooked manifestations

Research output: Chapter in Book/Report/Conference proceedingChapter


Systemic sclerosis (SSc) is a heterogeneous disease with well-described traditional clinical manifestations, such as Raynaud’s phenomenon, dermal sclerosis, esophageal dysmotility, calcinosis, and telangiectasia. Because the clinical presentation can be complex and involve multiple organ systems, there are several other manifestations that often go unrecognized but cause significant morbidity. This chapter discusses a few such manifestations, including neurological manifestations, audiovestibular disease, oral complications, thyroid dysfunction, liver disease, avascular necrosis of bone, bladder dysfunction, and erectile dysfunction.

Original languageEnglish (US)
Title of host publicationScleroderma
Subtitle of host publicationFrom Pathogenesis to Comprehensive Management
PublisherSpringer International Publishing
Number of pages18
ISBN (Electronic)9783319314075
ISBN (Print)9783319314051
StatePublished - Jan 1 2016


  • Autoimmune hepatitis
  • Erectile dysfunction
  • Hypothyroidism
  • Microstomia
  • Neuropathy
  • Primary biliary cirrhosis
  • Sensorineural hearing loss
  • Urinary tract disease
  • Xerostomia

ASJC Scopus subject areas

  • General Medicine


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