Outcomes in Patients with Minor Stroke: Diagnosis and Management in the Post-thrombectomy Era

Elisabeth B. Marsh, Sophia Girgenti, Edward J. Llinas, Autumn O. Brunson

Research output: Contribution to journalReview articlepeer-review

Abstract

In the era of mechanical thrombectomy and better preventative strategies, a higher number of patients are being discharged home from the hospital with the so-called minor strokes. This has significantly changed the landscape of stroke recovery. Unfortunately, while symptoms may be categorized as mild compared to individuals with higher NIH Stroke Scale scores, the physical, cognitive, and emotional sequelae can be disabling and result in failure to return to work and poor quality of life in a population with significant potential to recover fully. In this review, we discuss the current state of minor stroke, the most common pattern of resulting deficits, what is known about the underlying pathophysiology that leads to a relatively global pattern of impaired cognition following an infarct in any location, and special considerations for treatment based on this population’s unique needs. Raising awareness of the current morbidity associated with minor stroke, the need for a uniform definition that allows for comparisons of individuals across studies, and further research focused on this population to optimize outcomes, has the potential to significantly improve recovery.

Original languageEnglish (US)
Pages (from-to)732-743
Number of pages12
JournalNeurotherapeutics
Volume20
Issue number3
DOIs
StatePublished - Apr 2023

Keywords

  • Cognitive decline
  • Depression
  • Minor stroke
  • Outcomes
  • Recovery

ASJC Scopus subject areas

  • Clinical Neurology
  • Pharmacology (medical)
  • Pharmacology

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