Osteogenesis imperfecta type II: Fetal magnetic resonance imaging findings

Alina Solopova, Josef Wisser, Thierry A G M Huisman

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


We describe the prenatal magnetic resonance imaging (MRI) findings in a 25-week-old fetus with proven osteogenesis imperfecta type II. Fetal MRI findings are correlated with prenatal ultrasonography, conventional x-ray fetography and postpartal findings. Fetal MRI proves to be superior to conventional fetography in the evaluation of the skeletal findings. The high soft tissue resolution, the large field of view and the multiplanar imaging make it possible to study the non-ossified fetal skeleton in detail. Compared to prenatal ultrasonography, fetal MRI gives important additional information about the expected lung functionality by estimating fetal lung volume and signal intensity and rules out possible additional abnormalities of major fetal organs. These parameters may serve as valuable, additional prognostic markers in the prenatal diagnostic work-up.

Original languageEnglish (US)
Pages (from-to)361-367
Number of pages7
JournalFetal Diagnosis and Therapy
Issue number4
StatePublished - Jan 2009


  • Fetal magnetic resonance imaging
  • Magnetic resonance fetography
  • Osteogenesis imperfecta
  • Prenatal diagnosis

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health
  • Embryology
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Osteogenesis imperfecta type II: Fetal magnetic resonance imaging findings'. Together they form a unique fingerprint.

Cite this