Organoids: A model for precision medicine

Noah S. Rozich; Alex B. Blair; Richard A. Burkhart

doi:10.1016/B978-0-12-819178-1.00012-5

Organoids: A model for precision medicine

Noah S. Rozich, Alex B. Blair, Richard A. Burkhart

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

An area of growing interest in precision medicine is the utilization of in vitro and in vivo models of diseases that are reliable and accurate representations. These model systems not only provide valuable insight into disease mechanism and pathophysiology, but also provide a platform with which to test and develop targeted therapeutic agents. The ability to tailor treatment for individual patients is truly reliant on the establishment of effective and efficient model systems. Thus, models that accurately recapitulate disease processes and reliably predict therapeutic efficacy are invaluable to moving the field of precision medicine forward.

Original language	English (US)
Title of host publication	Precision Medicine for Investigators, Practitioners and Providers
Publisher	Elsevier
Pages	123-129
Number of pages	7
ISBN (Electronic)	9780128191781
DOIs	https://doi.org/10.1016/B978-0-12-819178-1.00012-5
State	Published - Jan 1 2019

Keywords

3D culture systems
Biobanks
Cell culture
Cellular heterogeneity
Disease models
Xenograft models

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/B978-0-12-819178-1.00012-5

Cite this

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KW - Cellular heterogeneity

KW - Disease models

KW - Xenograft models

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Organoids: A model for precision medicine

Abstract

Keywords

ASJC Scopus subject areas

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