Oral Pemphigus Vulgaris After SARS-CoV-2 Vaccine: A Case Report and Review of Literature

Tammy Nunez; Antonio Salas; Ayotola Fatola; Neda F. Gould; Rebecca Krimins; Homa Timlin

doi:10.7326/aimcc.2023.0866

Oral Pemphigus Vulgaris After SARS-CoV-2 Vaccine: A Case Report and Review of Literature

Tammy Nunez, Antonio Salas, Ayotola Fatola, Neda F. Gould, Rebecca Krimins, Homa Timlin

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Pemphigus vulgaris is an antibody-mediated autoimmune disease that causes blistering of the skin and mucus membranes. A variety of environmental factors have been suggested as triggers to pemphigus exacerbations, including ultraviolet radiation, trauma, drugs, viral and bacterial vaccination. We present a patient who developed oral lesions shortly after the administration of the SARS-CoV-2 vaccine. Biopsy of the oral mucosa revealed pemphigus vulgaris, and the patient was managed with immunosuppressants.

Original language	English (US)
Article number	e230866
Journal	Annals of Internal Medicine Clinical Cases
Volume	3
Issue number	5
DOIs	https://doi.org/10.7326/aimcc.2023.0866
State	Published - May 2024

Keywords

Blisters
Case reports
COVID
COVID-19
Desmoglein
Genetic predisposition
Immune response
Lesions
Mucous membranes
Oral medicine
Pemphigus vulgaris
Skin
Vaccines

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Internal Medicine
Clinical Biochemistry

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10.7326/aimcc.2023.0866

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title = "Oral Pemphigus Vulgaris After SARS-CoV-2 Vaccine: A Case Report and Review of Literature",

abstract = "Pemphigus vulgaris is an antibody-mediated autoimmune disease that causes blistering of the skin and mucus membranes. A variety of environmental factors have been suggested as triggers to pemphigus exacerbations, including ultraviolet radiation, trauma, drugs, viral and bacterial vaccination. We present a patient who developed oral lesions shortly after the administration of the SARS-CoV-2 vaccine. Biopsy of the oral mucosa revealed pemphigus vulgaris, and the patient was managed with immunosuppressants.",

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AB - Pemphigus vulgaris is an antibody-mediated autoimmune disease that causes blistering of the skin and mucus membranes. A variety of environmental factors have been suggested as triggers to pemphigus exacerbations, including ultraviolet radiation, trauma, drugs, viral and bacterial vaccination. We present a patient who developed oral lesions shortly after the administration of the SARS-CoV-2 vaccine. Biopsy of the oral mucosa revealed pemphigus vulgaris, and the patient was managed with immunosuppressants.

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Oral Pemphigus Vulgaris After SARS-CoV-2 Vaccine: A Case Report and Review of Literature

Abstract

Keywords

ASJC Scopus subject areas

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