Oral antibiotics in the nineties: new drugs and new challenges in primary care.

R. A. Bonomo, J. Aucott, R. A. Salata

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


The primary care physician is faced with a bewildering array of new oral antimicrobials to treat common infections. These agents promise to be extremely effective as replacements for time-honored drugs, as prophylaxis, and for the treatment of infections previously requiring prolonged intravenous therapy. The overuse of the newer macrolides, quinolones, and beta-lactam beta-lactamase inhibitors may prove to be ecologically and economically costly. It is feared that the selective pressure from these broad spectrum agents may burden society with an even greater problem of multiply resistant community-acquired pathogens. The specific therapeutic and economic advantages and disadvantages of each class should be considered and the decision to employ these agents should be highly individualized.

Original languageEnglish (US)
Pages (from-to)e63-71
JournalFrontiers in bioscience : a journal and virtual library
StatePublished - Aug 15 1997
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology


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