Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging

Wu Yuan; Jessica Mavadia-Shukla; Jiefeng Xi; Wenxuan Liang; Xiaoyun Yu; Shaoyong Yu; Xingde Li

doi:10.1364/OL.41.000250

Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging

Wu Yuan, Jessica Mavadia-Shukla, Jiefeng Xi, Wenxuan Liang, Xiaoyun Yu, Shaoyong Yu, Xingde Li

School of Medicine

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

We investigated the optimal operational conditions for utilizing a broadband supercontinuum (SC) source in a portable 800 nm spectral-domain (SD) endoscopic OCT system to enable high resolution, high-sensitivity, and high-speed imaging in vivo. A SC source with a 3-dB bandwidth of ∼246 nm was employed to obtain an axial resolution of ∼2.7 μm (in air) and an optimal detection sensitivity of ∼ - 107 dB with an imaging speed up to 35 frames/s (at 70 k A-scans/s). The performance of the SC-based SD-OCT endoscopy system was demonstrated by imaging Guinea pig esophagus in vivo, achieving image quality comparable to that acquired with a broadband home-built Ti:sapphire laser.

Original language	English (US)
Pages (from-to)	250-253
Number of pages	4
Journal	Optics Letters
Volume	41
Issue number	2
DOIs	https://doi.org/10.1364/OL.41.000250
State	Published - Jan 15 2016

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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abstract = "We investigated the optimal operational conditions for utilizing a broadband supercontinuum (SC) source in a portable 800 nm spectral-domain (SD) endoscopic OCT system to enable high resolution, high-sensitivity, and high-speed imaging in vivo. A SC source with a 3-dB bandwidth of ∼246 nm was employed to obtain an axial resolution of ∼2.7 μm (in air) and an optimal detection sensitivity of ∼ - 107 dB with an imaging speed up to 35 frames/s (at 70 k A-scans/s). The performance of the SC-based SD-OCT endoscopy system was demonstrated by imaging Guinea pig esophagus in vivo, achieving image quality comparable to that acquired with a broadband home-built Ti:sapphire laser.",

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AU - Xi, Jiefeng

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AU - Yu, Xiaoyun

AU - Yu, Shaoyong

AU - Li, Xingde

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Optimal operational conditions for supercontinuum-based ultrahigh-resolution endoscopic OCT imaging

Abstract

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