Optical coherence tomography angiography imaging in inherited retinal diseases

Sally S. Ong, Tapan P. Patel, Mandeep S. Singh

Research output: Contribution to journalReview articlepeer-review


Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies. In this review, we provide an overview of the evolution of OCTA technology, compare the specifications of various OCTA devices, and summarize key findings from published OCTA studies in inherited retinal dystrophies including retinitis pigmentosa, Stargardt disease, Best vitelliform macular dystrophy, and choroideremia. OCTA imaging has provided new data on characteristics of these conditions and has contributed to a deeper understanding of inherited retinal disease.

Original languageEnglish (US)
Article number2078
JournalJournal of Clinical Medicine
Issue number12
StatePublished - 2019


  • Best disease
  • Choriocapillaris
  • Choroideremia
  • Degenerative retinal diseases
  • Gene therapy
  • In vivo imaging
  • Optical coherence tomography angiography
  • Retinal pigment epithelium
  • Retinitis pigmentosa
  • Stargardt disease

ASJC Scopus subject areas

  • General Medicine


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