Optic neuritis

Amanda D. Henderson

doi:10.1007/978-3-030-74103-7_4

Optic neuritis

Amanda D. Henderson

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Optic neuritis is an inflammatory optic neuropathy that typically presents with acute to subacute vision loss associated with pain exacerbated by eye movements. While it can be isolated, optic neuritis commonly is associated with an underlying systemic condition, such as multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein-associated disorder. Correct diagnosis of these conditions is crucial to permit optimal treatment and accurate prognostication. Clinical presentation and neuroimaging characteristics may help guide clinical suspicion and, thus, further evaluation. Serum and cerebrospinal fluid testing also may contribute to the ultimate diagnosis of the underlying condition.

Original language	English (US)
Title of host publication	Controversies in Neuro-Ophthalmic Management
Subtitle of host publication	An Evidence and Case-Based Appraisal
Publisher	Springer International Publishing
Pages	25-39
Number of pages	15
ISBN (Electronic)	9783030741037
ISBN (Print)	9783030741020
DOIs	https://doi.org/10.1007/978-3-030-74103-7_4
State	Published - Jun 25 2021

Keywords

Aquaporin-4 antibodies
Magnetic resonance imaging (MRI)
MOG-IgG
Multiple sclerosis
Myelin oligodendrocyte glycoprotein
Neuromyelitis optica spectrum disorder
Optic neuritis

ASJC Scopus subject areas

General Medicine

Access to Document

10.1007/978-3-030-74103-7_4

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title = "Optic neuritis",

abstract = "Optic neuritis is an inflammatory optic neuropathy that typically presents with acute to subacute vision loss associated with pain exacerbated by eye movements. While it can be isolated, optic neuritis commonly is associated with an underlying systemic condition, such as multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein-associated disorder. Correct diagnosis of these conditions is crucial to permit optimal treatment and accurate prognostication. Clinical presentation and neuroimaging characteristics may help guide clinical suspicion and, thus, further evaluation. Serum and cerebrospinal fluid testing also may contribute to the ultimate diagnosis of the underlying condition.",

keywords = "Aquaporin-4 antibodies, Magnetic resonance imaging (MRI), MOG-IgG, Multiple sclerosis, Myelin oligodendrocyte glycoprotein, Neuromyelitis optica spectrum disorder, Optic neuritis",

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N2 - Optic neuritis is an inflammatory optic neuropathy that typically presents with acute to subacute vision loss associated with pain exacerbated by eye movements. While it can be isolated, optic neuritis commonly is associated with an underlying systemic condition, such as multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein-associated disorder. Correct diagnosis of these conditions is crucial to permit optimal treatment and accurate prognostication. Clinical presentation and neuroimaging characteristics may help guide clinical suspicion and, thus, further evaluation. Serum and cerebrospinal fluid testing also may contribute to the ultimate diagnosis of the underlying condition.

AB - Optic neuritis is an inflammatory optic neuropathy that typically presents with acute to subacute vision loss associated with pain exacerbated by eye movements. While it can be isolated, optic neuritis commonly is associated with an underlying systemic condition, such as multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein-associated disorder. Correct diagnosis of these conditions is crucial to permit optimal treatment and accurate prognostication. Clinical presentation and neuroimaging characteristics may help guide clinical suspicion and, thus, further evaluation. Serum and cerebrospinal fluid testing also may contribute to the ultimate diagnosis of the underlying condition.

KW - Aquaporin-4 antibodies

KW - Magnetic resonance imaging (MRI)

KW - MOG-IgG

KW - Multiple sclerosis

KW - Myelin oligodendrocyte glycoprotein

KW - Neuromyelitis optica spectrum disorder

KW - Optic neuritis

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SP - 25

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BT - Controversies in Neuro-Ophthalmic Management

PB - Springer International Publishing

ER -

Optic neuritis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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