Opportunities and challenges for dietary arsenic intervention

Keeve E. Nachman, Tracy Punshon, Laurie Rardin, Antonio J. Signes-Pastor, Carolyn J. Murray, Brian P. Jackson, Mary Lou Guerinot, Thomas A. Burke, Celia Y. Chen, Habibul Ahsan, Maria Argos, Kathryn L. Cottingham, Francesco Cubadda, Gary L. Ginsberg, Britton C. Goodale, Margaret Kurzius-Spencer, Andrew A. Meharg, Mark D. Miller, Anne E. Nigra, Claire B. PendergrastAndrea Raab, Ken Reimer, Kirk G. Scheckel, Tanja Schwerdtle, Vivien F. Taylor, Erik J. Tokar, Todd M. Warczak, Margaret R. Karagas

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


SUMMARY: The diet is emerging as the dominant source of arsenic exposure for most of the U.S. population. Despite this, limited regulatory efforts have been aimed at mitigating exposure, and the role of diet in arsenic exposure and disease processes remains understudied. In this brief, we discuss the evidence linking dietary arsenic intake to human disease and discuss challenges associated with exposure characterization and efforts to quantify risks. In light of these challenges, and in recognition of the potential longer-term process of establishing regulation, we introduce a framework for shorter-term interventions that employs a field-to-plate food supply chain model to identify monitoring, intervention, and communication opportunities as part of a multisector, multiagency, science-informed, public health systems approach to mitigation of dietary arsenic exposure. Such an approach is dependent on coordination across commodity producers, the food industry, nongovernmental organizations, health professionals, researchers, and the regulatory community.

Original languageEnglish (US)
Article number084503
JournalEnvironmental health perspectives
Issue number8
StatePublished - Aug 2018

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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