Operant conditioning of heart rate in patients with premature ventricular contractions

T. Weiss, B. T. Engel

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Operant conditioning of heart rate (HR) was carried out in 8 patients with premature ventricular concentrations (PVCs). All of the patients showed some degree of HR control. Five of these patients showed a decrease in PVCs in association with the learning of HR control. Four patients have shown persistence of a low PVC frequency after study, the longest followup being 21 mth. Pharmacologic studies suggested that decreased PVC frequency was mediated by diminished sympathetic tone in 1 patient and increased vagal tone in another. These findings suggest that some aspects of cardiac ventricular function can be brought under voluntary control. Once such control has been acquired, it can mediate clinically significant changes in cardiac function.

Original languageEnglish (US)
Pages (from-to)439-460
Number of pages22
Issue number4
StatePublished - Dec 1 1973

ASJC Scopus subject areas

  • General Medicine


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