Abstract
The human genome contains a large number of endogenous retroviral-related sequences. While the function of these sequences is unknown, they may contribute to disease processes through their regions of homology with infectious retroviruses. We have been further characterizing a recently reported HTLV-1 related endogenous retroviral sequence cloned from T lymphocytes isolated from a patient with essential cryoglobulinemia. We here report further detailed transcriptional analysis of the sequence for tissue and cell-cycle specificity and a novel finding of an association between the endogenous retrovirus and a ras-related gene.
Original language | English (US) |
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Pages (from-to) | 113-122 |
Number of pages | 10 |
Journal | Acta virologica |
Volume | 37 |
Issue number | 2-3 |
State | Published - 1993 |
Externally published | Yes |
ASJC Scopus subject areas
- Virology
- Infectious Diseases