Olfactory dysfunction and face processing of social cognition in first-episode psychosis

Semra Etyemez, Zui Narita, Marina Mihaljevic, Koko Ishizuka, Vidyulata Kamath, Kun Yang, Akira Sawa

Research output: Contribution to journalArticlepeer-review

Abstract

Olfactory functional deficits have been reported in psychotic disorders. Olfactory dysfunction has a predictive value for prognosis and disease course. Thus, it is important to know which specific symptoms and cognitive changes are associated with olfactory dysfunction in early-stage psychosis. Deficits in social cognition are a difficult problem in psychosis. Here we conduct a detailed assessment of odor function and face processing and show that odor discrimination capacity is specifically associated with face processing function in patients with first episode psychosis. This finding indicates that the high-throughput olfactory assessment may aid a prediction of the difficult clinical dimension from early-stage psychosis.

Original languageEnglish (US)
Pages (from-to)79-84
Number of pages6
JournalNeuroscience Research
Volume176
DOIs
StatePublished - Mar 2022

Keywords

  • Face processing
  • First episode psychosis
  • Olfactory dysfunction
  • Schizophrenia
  • Social cognition

ASJC Scopus subject areas

  • General Neuroscience

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