Olfactory bulb and tract and temporal lobe volumes. Normative data across decades

David M. Yousem, Rena J. Geckle, Warren B. Bilker, Richard L. Doty

Research output: Contribution to journalArticlepeer-review

104 Scopus citations


The sense of smell shows a diminution with age as measured by the University of Pennsylvania Smell Identification Test (UPSIT). To ascertain whether the volumes of the olfactory bulbs and tracts (OBTs) and the temporal lobes (TL) declined in parallel to smell function, we examined 35 individuals from ages 22 to 78 who did not complain of any loss of the sense of smell using magnetic resonance (MR) imaging. The OBT volumes showed an initial increase to the 4th decade of life and then a decrease with increasing age, while the trend in TL volume was not as dramatic. There was no correlation between OBT or TL volumes with unilateral or total UPSIT scores. The normative data by decades can be used to assess the OBTs of cohorts of patients with neurodegenerative disorders that affect olfaction.

Original languageEnglish (US)
Pages (from-to)546-555
Number of pages10
JournalAnnals of the New York Academy of Sciences
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science


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