Of mice, men, women, and cancer

Alice L. Mueller; Sabra L. Klein

doi:10.1016/j.immuni.2022.06.009

Of mice, men, women, and cancer

Alice L. Mueller, Sabra L. Klein

Bloomberg School of Public Health

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

The prevalence and severity of cancers in non-reproductive tissues are greater in males than females, but the sex-specific factors contributing to this remain ill described. In this issue of Immunity, Yang et al. (2022) uncover a mechanism of androgen signaling leading to an exhausted, terminally differentiated CD8⁺ T cell phenotype in male mice.

Original language	English (US)
Pages (from-to)	1150-1152
Number of pages	3
Journal	Immunity
Volume	55
Issue number	7
DOIs	https://doi.org/10.1016/j.immuni.2022.06.009
State	Published - Jul 12 2022

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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10.1016/j.immuni.2022.06.009

Cite this

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title = "Of mice, men, women, and cancer",

abstract = "The prevalence and severity of cancers in non-reproductive tissues are greater in males than females, but the sex-specific factors contributing to this remain ill described. In this issue of Immunity, Yang et al. (2022) uncover a mechanism of androgen signaling leading to an exhausted, terminally differentiated CD8+ T cell phenotype in male mice.",

author = "Mueller, {Alice L.} and Klein, {Sabra L.}",

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AU - Klein, Sabra L.

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AB - The prevalence and severity of cancers in non-reproductive tissues are greater in males than females, but the sex-specific factors contributing to this remain ill described. In this issue of Immunity, Yang et al. (2022) uncover a mechanism of androgen signaling leading to an exhausted, terminally differentiated CD8+ T cell phenotype in male mice.

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Of mice, men, women, and cancer

Abstract

ASJC Scopus subject areas

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