Ocular surface disease in thyroid eye disease: A narrative review

Harkaran S. Rana; Sruti S. Akella; Carson E. Clabeaux; Zachary P. Skurski; Vinay K. Aakalu

doi:10.1016/j.jtos.2022.02.001

Ocular surface disease in thyroid eye disease: A narrative review

Harkaran S. Rana, Sruti S. Akella, Carson E. Clabeaux, Zachary P. Skurski, Vinay K. Aakalu

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Ocular surface disease (OSD) in the setting of thyroid eye disease (TED) is traditionally thought of as a natural consequence of anatomical changes such as proptosis and corneal exposure. However, a growing body of research suggests that ocular surface inflammation and multi-factorial changes to the homeostasis of the ocular surface contribute substantially to the OSD seen in TED patients. In this paper we review the existing literature which highlights the work and existing theories underlying this new paradigm shift.

Original language	English (US)
Pages (from-to)	67-73
Number of pages	7
Journal	Ocular Surface
Volume	24
DOIs	https://doi.org/10.1016/j.jtos.2022.02.001
State	Published - Apr 2022

Keywords

Dry eye
Exposure keratopathy
Ocular surface disease
Thyroid eye disease

ASJC Scopus subject areas

Ophthalmology

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10.1016/j.jtos.2022.02.001

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@article{1ac27fda4545443eab01471571c142fc,

title = "Ocular surface disease in thyroid eye disease: A narrative review",

abstract = "Ocular surface disease (OSD) in the setting of thyroid eye disease (TED) is traditionally thought of as a natural consequence of anatomical changes such as proptosis and corneal exposure. However, a growing body of research suggests that ocular surface inflammation and multi-factorial changes to the homeostasis of the ocular surface contribute substantially to the OSD seen in TED patients. In this paper we review the existing literature which highlights the work and existing theories underlying this new paradigm shift.",

keywords = "Dry eye, Exposure keratopathy, Ocular surface disease, Thyroid eye disease",

author = "Rana, {Harkaran S.} and Akella, {Sruti S.} and Clabeaux, {Carson E.} and Skurski, {Zachary P.} and Aakalu, {Vinay K.}",

note = "Funding Information: This work was supposed by the National Eye Institute (P30EY001792, R01EY029409); Research to Prevent Blindness, New York, NY. Publisher Copyright: {\textcopyright} 2022",

year = "2022",

month = apr,

doi = "10.1016/j.jtos.2022.02.001",

language = "English (US)",

volume = "24",

pages = "67--73",

journal = "Ocular Surface",

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T2 - A narrative review

AU - Rana, Harkaran S.

AU - Akella, Sruti S.

AU - Clabeaux, Carson E.

AU - Skurski, Zachary P.

AU - Aakalu, Vinay K.

PY - 2022/4

Y1 - 2022/4

N2 - Ocular surface disease (OSD) in the setting of thyroid eye disease (TED) is traditionally thought of as a natural consequence of anatomical changes such as proptosis and corneal exposure. However, a growing body of research suggests that ocular surface inflammation and multi-factorial changes to the homeostasis of the ocular surface contribute substantially to the OSD seen in TED patients. In this paper we review the existing literature which highlights the work and existing theories underlying this new paradigm shift.

AB - Ocular surface disease (OSD) in the setting of thyroid eye disease (TED) is traditionally thought of as a natural consequence of anatomical changes such as proptosis and corneal exposure. However, a growing body of research suggests that ocular surface inflammation and multi-factorial changes to the homeostasis of the ocular surface contribute substantially to the OSD seen in TED patients. In this paper we review the existing literature which highlights the work and existing theories underlying this new paradigm shift.

KW - Dry eye

KW - Exposure keratopathy

KW - Ocular surface disease

KW - Thyroid eye disease

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VL - 24

SP - 67

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JO - Ocular Surface

JF - Ocular Surface

ER -

Ocular surface disease in thyroid eye disease: A narrative review

Abstract

Keywords

ASJC Scopus subject areas

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