@article{e4825fc763a44850b1718d0c97b03b76,
title = "Ocular histopathologic studies of neonatal and childhood adrenoleukodystrophy",
abstract = "Histopathologic studies of the eyes of one patient (a boy who died at 14 years of age) with childhood adrenoleukodystrophy and two patients (girls who died at 24 and 31 months of age) with neonatal adrenoleukodystrophy showed the accumulation of the characteristic bileaflet inclusions in optic nerve macrophages, retinal neurons, and macrophages and loss of ganglion cell and nerve fiber layer. Additionally, in the two cases of neonatal adrenoleukodystrophy, changes resembling early retinitis pigmentosa were found, with accumulation of characteristic inclusions in the retinal pigment epithelium and pigment-laden macrophages. One of the patients with neonatal adrenoleukodystrophy also had an anterior subcapsular cataract and cystoid macular edema.",
author = "Cohen, {Sander M.Z.} and {Richard Green}, W. and {C.de la Cruz}, Zenaida and Brown, {Frank R.} and Moser, {Hugo W.} and Luckenbach, {Martha W.} and Dove, {Douglas J.} and Maumenee, {Irene H.}",
note = "Funding Information: From the Eye Pathology Laboratory, Wilmer Ophthalmological Institute (Mr. Cohen, Drs. Green, Luckenbach, and Maumenee, and Ms. de la Cruz), the Department of Pathology (Dr. Green), and the John F. Kennedy Institute (Drs. Brown and Moser), Johns Hopkins Medical Institutions, Baltimore, Maryland; and the Departments of Pediatrics and Neurology, Southern Illinois University School of Medicine, Springfield, Illinois (Dr. Dove). This study was supported in part by research grants 01684 (Dr. Green) and EY 01773 (Dr. Maumenee) from the National Eye Institute and by Public Health Service Biomedicai Research Support Grant RR 05378-20 (Mr. Cohen). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "1983",
month = jan,
doi = "10.1016/0002-9394(83)90336-7",
language = "English (US)",
volume = "95",
pages = "82--96",
journal = "American journal of ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "1",
}