Nutritional outcomes following gastrostomy in children with cystic fibrosis

Gia M. Bradley, Kathryn A. Carson, Amanda R. Leonard, Peter J. Mogayzel, Maria Oliva-Hemker

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Objective In 2005 the Cystic Fibrosis (CF) Foundation recommended that children with CF maintain a body mass index (BMI) ≥50th percentile. Our study evaluated if gastrostomy (GT) placement increases the likelihood of reaching that goal compared to a standardized nutrition protocol. Study design Retrospective study of 20 children with CF ages 2-20 years with GTs placed from 2005 to 2010. Each case was pair-matched on age, sex, pancreatic status, BMI, and lung function with a nonGT child with CF. Outcome measures included nutritional status and lung function at 6 months and 1 year. Results At baseline, mean ± SD BMI Z-scores were similar (cases -1.19 ± 0.60, controls -1.10 ± 0.50; P = 0.10). Cases had a significant 6-month increase in mean BMI Z-score to -0.29 ± 0.84 compared to -1.02 ± 0.67 for controls (P < 0.001). By 1 year, the change in mean BMI Z-score was less different (cases -0.41 ± 0.76, controls -0.71 ± 0.51; P = 0.07). Both groups had stable lung function. From exact logistic regression analysis, the odds ratio for cases compared to controls of reaching BMI ≥50th percentile was 9.70 (95% CI: 1.05-484.7; P = 0.04) at 6 months and 3.65 (95%CI: 0.69-25.86; P = 0.16) at 1 year. Conclusion Our study suggests that children with CF who receive GTs are more likely to achieve BMI ≥50th percentile than matched children without GTs.

Original languageEnglish (US)
Pages (from-to)743-748
Number of pages6
JournalPediatric pulmonology
Issue number8
StatePublished - Aug 2012


  • body mass index
  • growth
  • lung function

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine


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