Abstract
Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, poorly differentiated form of squamous cell carcinoma caused by a chromosomal rearrangement of the NUT gene on chromosome 15. These tumors have a predilection for midline and paramidline structures of the upper aerodigestive tract and mediastinum and can affect patients across a broad age range, including children. In the current example, a 53 year old male presented with a mass originating in the left nasal cavity. The clinical, radiographic, and morphologic features of NMC are discussed.
Original language | English (US) |
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Pages (from-to) | 389-392 |
Number of pages | 4 |
Journal | Head and Neck Pathology |
Volume | 11 |
Issue number | 3 |
DOIs | |
State | Published - Sep 1 2017 |
Externally published | Yes |
Keywords
- NUT midline carcinoma
- Nasal
- Nasal cavity
- Nuclear protein of testis
- Radiology
- Sinonasal
- Undifferentiated carcinoma
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Otorhinolaryngology
- Oncology