Nuclear medicine: SPECT (Single-Photon Emission Computed Tomography)

Benjamin Tsui

Research output: Chapter in Book/Report/Conference proceedingChapter


Nuclear medicine can be defined as the practice of making patients radioactive for diagnostic and therapeutic purposes. The radioactivity is injected intravenously, rebreathed, or ingested. It is the internal circulation of radioactive material that distinguishes nuclear medicine from diagnostic radiology and radiation oncology in most of its forms. This section will examine only the diagnostic use and will concentrate on methods for detecting the radioactivity from outside the body without trauma to the patient. Diagnostic nuclear medicine is successful for two main reasons: (1) it can rely on the use of very small amounts of materials (picomolar concentrations in chemical terms) thus usually not having any effect on the processes being studied, and (2) the radionuclides being used can penetrate tissue and be detected outside the patient. Thus the materials can trace processes or “opacify” organs without affecting their function.

Original languageEnglish (US)
Title of host publicationMedical Imaging
Subtitle of host publicationPrinciples and Practices
PublisherCRC Press
ISBN (Electronic)9781439871034
ISBN (Print)9781439871027
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Physics and Astronomy(all)


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