Norplant® subdermal contraceptive system: Experience in Taiwan

Li Hui Tseng, Tzu Yao Lee, Yu Shih Yang, Tsang Ming Ko, Sou Ming Chuang

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


From November 1988 to December 1994, a total of 567 female volunteers were enrolled in Norplant® implant studies at the National Taiwan University Hospital. After a median follow-up of 29 months, only 3 of the 529 available cases became pregnant (a cumulative rate of 1.2 pregnancies per 100 users over 5 years). Chromosome analysis of 2 of the 3 abortuses revealed 46,XX/46,XX,inv(3) and 46,XX. Menstrual problems were the most common adverse effects and were also the main reason for discontinuation (65%, 108/166). The continuation rate was 90%, 78%, 70%, 61%, and 42% at the end of 1, 2, 3, 4, and 5 years after insertion, respectively. In the 21 patients who wished to become pregnant, fertility recurred soon after removal of the Norplant implants. The data suggested that the Norplant implants system is a highly effective, safe, and long-acting method of reversible contraception. It would be worthwhile to introduce this contraceptive system into Taiwan's family planning program.

Original languageEnglish (US)
Pages (from-to)177-180
Number of pages4
Issue number3
StatePublished - Mar 1996
Externally publishedYes


  • chromosomal abnormality
  • contraception
  • Norplant implants

ASJC Scopus subject areas

  • General Medicine
  • Obstetrics and Gynecology


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