Nontraumatic focal lesions of the spleen: Assessment of imaging and clinical evaluation

Pamela L. Caslowitz, Joseph D. Labs, Elliot K. Fishman, Stanley S. Siegelman

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Fifty-nine cases of nontraumatic splenic disease were reviewed to evaluate the roles of clinical findings, computed tomography, ultrasound, and radionuclide scanning in diagnosis and management. Patient groups included lymphoma (30 patients), infarct (11 patients), abscess (9 patients), cyst (5 patients), hemangioma (3 patients), and hamartoma (1 patient). In no case were clinical findings alone sufficient to diagnose a splenic lesion. Clinical and laboratory manifestations were nonspecific in all groups. Moreover, no radiologic study reliably diagnosed splenic lymphoma or leukemia. All other focal splenic lesions were consistently diagnosed noninvasively. Cross-sectional imaging was more useful than radioisotope scanning, and often provided adjunctive diagnosis of extrasplenic pathology. The superior detail, spatial resolution, and sensitivity of computed tomography made it the single most valuable diagnostic modality.

Original languageEnglish (US)
Pages (from-to)133-141
Number of pages9
JournalComputerized Medical Imaging and Graphics
Issue number2
StatePublished - Jan 1 1990


  • Computed tomography
  • Diagnosis
  • Spleen

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design


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