Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy

Paul A. Bottomley

doi:10.1126/science.4023711

Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved ³¹P NMR spectroscopy

Paul A. Bottomley

Research output: Contribution to journal › Article › peer-review

164 Scopus citations

Abstract

Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative concentrations of high-energy phosphate metabolites have been recorded noninvasively from the human heart in vivo. Spectral data were spatially localized by combining a pulsed magnetic field gradient with surface NMR excitation-detection coils. The location of the selected spectral region was determined by conventional proton NMR imaging immediately before examination by phosphorus-31 NMR spectroscopy.

Original language	English (US)
Pages (from-to)	769-772
Number of pages	4
Journal	Science
Volume	229
Issue number	4715
DOIs	https://doi.org/10.1126/science.4023711
State	Published - 1985
Externally published	Yes

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title = "Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy",

abstract = "Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative concentrations of high-energy phosphate metabolites have been recorded noninvasively from the human heart in vivo. Spectral data were spatially localized by combining a pulsed magnetic field gradient with surface NMR excitation-detection coils. The location of the selected spectral region was determined by conventional proton NMR imaging immediately before examination by phosphorus-31 NMR spectroscopy.",

author = "Bottomley, \{Paul A.\}",

year = "1985",

doi = "10.1126/science.4023711",

language = "English (US)",

volume = "229",

pages = "769--772",

journal = "Science",

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publisher = "American Association for the Advancement of Science",

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T1 - Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy

AU - Bottomley, Paul A.

PY - 1985

Y1 - 1985

N2 - Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative concentrations of high-energy phosphate metabolites have been recorded noninvasively from the human heart in vivo. Spectral data were spatially localized by combining a pulsed magnetic field gradient with surface NMR excitation-detection coils. The location of the selected spectral region was determined by conventional proton NMR imaging immediately before examination by phosphorus-31 NMR spectroscopy.

AB - Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative concentrations of high-energy phosphate metabolites have been recorded noninvasively from the human heart in vivo. Spectral data were spatially localized by combining a pulsed magnetic field gradient with surface NMR excitation-detection coils. The location of the selected spectral region was determined by conventional proton NMR imaging immediately before examination by phosphorus-31 NMR spectroscopy.

UR - https://www.scopus.com/pages/publications/0021832929

UR - https://www.scopus.com/pages/publications/0021832929#tab=citedBy

U2 - 10.1126/science.4023711

DO - 10.1126/science.4023711

M3 - Article

C2 - 4023711

AN - SCOPUS:0021832929

SN - 0036-8075

VL - 229

SP - 769

EP - 772

JO - Science

JF - Science

IS - 4715

ER -

Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved ³¹P NMR spectroscopy

Abstract

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