Nonepileptic seizures under levetiracetam therapy

Andrei Ignatenco; Shahar Arzy; Joseph Ghika; Didier Genoud; Peter W. Kaplan; Stanislav Groppa; Margitta Seeck

doi:10.1016/j.yebeh.2010.09.002

Nonepileptic seizures under levetiracetam therapy

Andrei Ignatenco, Shahar Arzy, Joseph Ghika, Didier Genoud, Peter W. Kaplan, Stanislav Groppa, Margitta Seeck

School of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We describe two patients with epilepsy who presented with nonepileptic seizures (NES) when started on levetiracetam (LEV), which disappeared or significantly decreased when LEV was discontinued. NES are traditionally attributed to psychic trauma often after physical or sexual abuse, whereas the psychiatric side effects of levetiracetam largely encompass depression, hallucinations, and psychosis. We conclude that NES are a rare side effect of LEV treatment and part of the spectrum of behavioral changes observed with LEV treatment.

Original language	English (US)
Pages (from-to)	526-527
Number of pages	2
Journal	Epilepsy and Behavior
Volume	19
Issue number	3
DOIs	https://doi.org/10.1016/j.yebeh.2010.09.002
State	Published - Nov 2010

Keywords

Anxiety
Depression
Levetiracetam
Nonepileptic seizures
Psychogenic seizures
Side effects
Tumor

ASJC Scopus subject areas

Neurology
Clinical Neurology
Behavioral Neuroscience

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10.1016/j.yebeh.2010.09.002

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title = "Nonepileptic seizures under levetiracetam therapy",

abstract = "We describe two patients with epilepsy who presented with nonepileptic seizures (NES) when started on levetiracetam (LEV), which disappeared or significantly decreased when LEV was discontinued. NES are traditionally attributed to psychic trauma often after physical or sexual abuse, whereas the psychiatric side effects of levetiracetam largely encompass depression, hallucinations, and psychosis. We conclude that NES are a rare side effect of LEV treatment and part of the spectrum of behavioral changes observed with LEV treatment.",

keywords = "Anxiety, Depression, Levetiracetam, Nonepileptic seizures, Psychogenic seizures, Side effects, Tumor",

author = "Andrei Ignatenco and Shahar Arzy and Joseph Ghika and Didier Genoud and Kaplan, {Peter W.} and Stanislav Groppa and Margitta Seeck",

note = "Funding Information: This work was supported by the following grants: SNF 320030-122073, 320030-113766, 320030-118385 , SPUM grants 33CM30-124089 , and 33CM30-124115 .",

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doi = "10.1016/j.yebeh.2010.09.002",

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journal = "Epilepsy and Behavior",

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T1 - Nonepileptic seizures under levetiracetam therapy

AU - Ignatenco, Andrei

AU - Arzy, Shahar

AU - Ghika, Joseph

AU - Genoud, Didier

AU - Kaplan, Peter W.

AU - Groppa, Stanislav

AU - Seeck, Margitta

N1 - Funding Information: This work was supported by the following grants: SNF 320030-122073, 320030-113766, 320030-118385 , SPUM grants 33CM30-124089 , and 33CM30-124115 .

PY - 2010/11

Y1 - 2010/11

N2 - We describe two patients with epilepsy who presented with nonepileptic seizures (NES) when started on levetiracetam (LEV), which disappeared or significantly decreased when LEV was discontinued. NES are traditionally attributed to psychic trauma often after physical or sexual abuse, whereas the psychiatric side effects of levetiracetam largely encompass depression, hallucinations, and psychosis. We conclude that NES are a rare side effect of LEV treatment and part of the spectrum of behavioral changes observed with LEV treatment.

AB - We describe two patients with epilepsy who presented with nonepileptic seizures (NES) when started on levetiracetam (LEV), which disappeared or significantly decreased when LEV was discontinued. NES are traditionally attributed to psychic trauma often after physical or sexual abuse, whereas the psychiatric side effects of levetiracetam largely encompass depression, hallucinations, and psychosis. We conclude that NES are a rare side effect of LEV treatment and part of the spectrum of behavioral changes observed with LEV treatment.

KW - Anxiety

KW - Depression

KW - Levetiracetam

KW - Nonepileptic seizures

KW - Psychogenic seizures

KW - Side effects

KW - Tumor

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JO - Epilepsy and Behavior

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IS - 3

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Nonepileptic seizures under levetiracetam therapy

Abstract

Keywords

ASJC Scopus subject areas

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