TY - JOUR
T1 - Nonalcoholic fatty liver disease as a component of the metabolic syndrome
AU - Khashab, Mouen A.
AU - Liangpunsakul, Suthat
AU - Chalasani, Naga
PY - 2008
Y1 - 2008
N2 - Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver-related morbidity and mortality. The association between NAFLD and the metabolic syndrome is well established: the presence of the metabolic syndrome signifies advanced histology in NAFLD patients. Emerging data indicate that patients with NAFLD have a significantly higher prevalence of cardiovascular disease. This article reviews the definitions of the two syndromes, their association, and the cardiovascular risk conferred by both when they occur separately and together. This review also discusses management options for the syndromes, including treating the individual components of the metabolic syndrome in NAFLD patients.
AB - Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver-related morbidity and mortality. The association between NAFLD and the metabolic syndrome is well established: the presence of the metabolic syndrome signifies advanced histology in NAFLD patients. Emerging data indicate that patients with NAFLD have a significantly higher prevalence of cardiovascular disease. This article reviews the definitions of the two syndromes, their association, and the cardiovascular risk conferred by both when they occur separately and together. This review also discusses management options for the syndromes, including treating the individual components of the metabolic syndrome in NAFLD patients.
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U2 - 10.1007/s11894-008-0012-0
DO - 10.1007/s11894-008-0012-0
M3 - Review article
C2 - 18417046
AN - SCOPUS:51549099280
SN - 1522-8037
VL - 10
SP - 73
EP - 80
JO - Current gastroenterology reports
JF - Current gastroenterology reports
IS - 1
ER -