Fc receptors (FcR) that are specific for particular immunoglobulin isotypes are designated by Greek letters. Subtypes of receptors are denoted by capital Roman numerals, such as: Fc(γ)RI, II and III: Fc receptors for IgG on macrophages/monocytes and lymphocytes (numerals are in the order of affinity for IgG); Fc(α)R, Fc(μ)R and Fc(δ)R: Fc receptors for IgA, IgM and IgD; Fc(ε)RI: high-affinity receptors for IgE on mast cells and basophils; Fc(ε)RII: low-affinity receptors for IgE on lymphocytes, macrophages, and activated eosinophils. Species are abbreviated as follows: hu (human), mo (mouse), rt (rat), and rb (rabbit). Subunits of receptors are designated by Greek letters α, β, γ and transcripts by a, b, c, etc. Ig-BF describes the soluble molecules having affinity for immunoglobulin.
|Original language||English (US)|
|Number of pages||2|
|Journal||Bulletin of the World Health Organization|
|State||Published - 1989|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health