Nitric oxide monitoring in hippocampal brain slices

R. Rangarajan, L. J. Johnson, N. C. Yang, N. V. Thakor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nitric Oxide (NO) is known to mediate the excitotoxic injury caused due to overactivation of N-Methyl-D-Aspartate (NMDA) receptors. NO production in response to NMDA receptor activation is studied in three hippocampal subregions: the CA1, CA3 and the Dentate Gyrus (DG). These three regions are differentially sensitive to NMDA toxicity, with the degree of response being the highest in CA1 and the lowest in DG. The results show that the NO production in these regions is different and consistent with their sensitivity to NMDA.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Pages365
Number of pages1
ISBN (Print)0780356756
StatePublished - 1999
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume1
ISSN (Print)0589-1019

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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