TY - JOUR
T1 - Nitric oxide metabolite production in the human preimplantation embryo and successful blastocyst formation
AU - Lipari, Christopher W.
AU - Garcia, Jairo E.
AU - Zhao, Yulian
AU - Thrift, Kimberly
AU - Vaidya, Dhananjay
AU - Rodriguez, Annabelle
PY - 2009/4
Y1 - 2009/4
N2 - Eleven patients underwent controlled ovarian hyperstimulation yielding 72 embryos for evaluation. Mean nitric oxide metabolite levels in the insemination media were 2.6 times higher in embryos that progressed to blastocysts by culture day 5 than in those that did not. A comparison of the receiver operating characteristic curves between morphological predictors and nitric oxide metabolite levels revealed a trend toward a stronger association of insemination media nitric oxide metabolite with blastocyst formation.
AB - Eleven patients underwent controlled ovarian hyperstimulation yielding 72 embryos for evaluation. Mean nitric oxide metabolite levels in the insemination media were 2.6 times higher in embryos that progressed to blastocysts by culture day 5 than in those that did not. A comparison of the receiver operating characteristic curves between morphological predictors and nitric oxide metabolite levels revealed a trend toward a stronger association of insemination media nitric oxide metabolite with blastocyst formation.
UR - http://www.scopus.com/inward/record.url?scp=63249131616&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=63249131616&partnerID=8YFLogxK
U2 - 10.1016/j.fertnstert.2008.01.108
DO - 10.1016/j.fertnstert.2008.01.108
M3 - Article
C2 - 18377900
AN - SCOPUS:63249131616
SN - 0015-0282
VL - 91
SP - 1316
EP - 1318
JO - Fertility and sterility
JF - Fertility and sterility
IS - 4 SUPPL.
ER -