TY - JOUR
T1 - Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014
AU - Hassan, Md Zakiul
AU - Sazzad, Hossain M.S.
AU - Luby, Stephen P.
AU - Sturm-Ramirez, Katharine
AU - Bhuiyan, Mejbah Uddin
AU - Rahman, Mohammed Ziaur
AU - Islam, Md Muzahidul
AU - Ströher, Ute
AU - Sultana, Sharmin
AU - Kafi, Mohammad Abdullah Heel
AU - Daszak, Peter
AU - Rahman, Mahmudur
AU - Gurley, Emily S.
N1 - Funding Information:
We thank all the study participants and their family members for their support during the investigation. We also thank the hospital authority for its permission and cooperation and the study physicians, field staff, and laboratory staff for their contributions. We are indebted to Diana Diaz Granados for reviewing and editing this manuscript. The study was funded by Centers for Disease Control and Prevention (CDC) cooperative agreement no. 5U01CI000628, US National Institutes of Health (NIH) grant no. 07-015-0712-52200 (Bangladesh-NIH/Emerging Infectious Diseases), and National Science Foundation/NIH Ecology and Evolution of Infectious Diseases grant no. 2R01-TW005869 from the Fogarty International Center. icddr,b acknowledges with gratitude the commitment of Centers for Disease Control and Prevention and NIH to its research effort. icddr,b is also grateful to the governments of Bangladesh, Canada, Sweden, and the United Kingdom for providing core/unrestricted support.
Funding Information:
The study was funded by Centers for Disease Control and Prevention (CDC) cooperative agreement no. 5U01CI000628, US National Institutes of Health (NIH) grant no. 07-015-0712-52200 (Bangladesh-NIH/Emerging Infectious Diseases), and National Science Foundation/NIH Ecology and Evolution of Infectious Diseases grant no. 2R01-TW005869 from the Fogarty International Center. icddr,b acknowledges with gratitude the commitment of Centers for Disease Control and Prevention and NIH to its research effort. icddr,b is also grateful to the governments of Bangladesh, Canada, Sweden, and the United Kingdom for providing core/unrestricted support.
Publisher Copyright:
© 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2018/1
Y1 - 2018/1
N2 - Nipah virus (NiV) has been transmitted from patient to caregivers in Bangladesh presumably through oral secretions. We aimed to detect whether NiV-infected patients contaminate hospital surfaces with the virus. During December 2013-April 2014, we collected 1 swab sample from 5 surfaces near NiV-infected patients and tested surface and oral swab samples by real-time reverse transcription PCR for NiV RNA. We identified 16 Nipah patients; 12 cases were laboratory-confirmed and 4 probable. Of the 12 laboratory-confirmed cases, 10 showed NiV RNA in oral swab specimens. We obtained surface swab samples for 6 Nipah patients; 5 had evidence of NiV RNA on >1 surface: 4 patients contaminated towels, 3 bed sheets, and 1 the bed rail. Patients with NiV RNA in oral swab samples were significantly more likely than other Nipah patients to die. To reduce the risk for fomite transmission of NiV, infection control should target hospital surfaces.
AB - Nipah virus (NiV) has been transmitted from patient to caregivers in Bangladesh presumably through oral secretions. We aimed to detect whether NiV-infected patients contaminate hospital surfaces with the virus. During December 2013-April 2014, we collected 1 swab sample from 5 surfaces near NiV-infected patients and tested surface and oral swab samples by real-time reverse transcription PCR for NiV RNA. We identified 16 Nipah patients; 12 cases were laboratory-confirmed and 4 probable. Of the 12 laboratory-confirmed cases, 10 showed NiV RNA in oral swab specimens. We obtained surface swab samples for 6 Nipah patients; 5 had evidence of NiV RNA on >1 surface: 4 patients contaminated towels, 3 bed sheets, and 1 the bed rail. Patients with NiV RNA in oral swab samples were significantly more likely than other Nipah patients to die. To reduce the risk for fomite transmission of NiV, infection control should target hospital surfaces.
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U2 - 10.3201/eid2401.161758
DO - 10.3201/eid2401.161758
M3 - Article
C2 - 29260663
AN - SCOPUS:85038821679
SN - 1080-6040
VL - 24
SP - 15
EP - 21
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 1
ER -