New strategies for enhancing the immunogenicity of tumors

Drew M. Pardoll

doi:10.1016/0952-7915(93)90127-E

New strategies for enhancing the immunogenicity of tumors

Drew M. Pardoll

School of Medicine

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Abstract

When a cancer grows in an individual, the immune system has either failed to recognize its antigens or failed to effectively respond. Increasing evidence for the existence of tumor antigens that are recognized by T cells provides a direct rationale for the design of novel strategies to either enhance tumor immunogenicity by genetic modification or utilize recombinant or peptide vaccines in cases where the relevant tumor antigens have been specifically identified.

Original language	English (US)
Pages (from-to)	719-725
Number of pages	7
Journal	Current Opinion in Immunology
Volume	5
Issue number	5
DOIs	https://doi.org/10.1016/0952-7915(93)90127-E
State	Published - Oct 1993

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/0952-7915(93)90127-E

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title = "New strategies for enhancing the immunogenicity of tumors",

abstract = "When a cancer grows in an individual, the immune system has either failed to recognize its antigens or failed to effectively respond. Increasing evidence for the existence of tumor antigens that are recognized by T cells provides a direct rationale for the design of novel strategies to either enhance tumor immunogenicity by genetic modification or utilize recombinant or peptide vaccines in cases where the relevant tumor antigens have been specifically identified.",

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New strategies for enhancing the immunogenicity of tumors

Abstract

ASJC Scopus subject areas

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