New prognostic factors for breast cancer recurrence

Claudine Isaacs, Vered Stearns, Daniel F. Hayes

Research output: Contribution to journalArticlepeer-review

85 Scopus citations


Decisions regarding the use of adjuvant therapy for breast cancer are strongly influenced by the risk of disease recurrence and death. These risks are now determined by examining the currently recognized breast cancer prognostic factors including clinical stage, axillary nodal status, tumor size and grade, hormone receptor status, and presence of lymphovascular involvement. Newer factors are being evaluated in an attempt to more precisely define disease-related prognosis. This article provides an overview of issues that need to be considered when analyzing studies of prognostic factors, as well as a review of the currently recognized and the newer candidate prognostic factors.

Original languageEnglish (US)
Pages (from-to)53-67
Number of pages15
JournalSeminars in oncology
Issue number1
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Hematology
  • Oncology


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