TY - JOUR
T1 - New prognostic factors for breast cancer recurrence
AU - Isaacs, Claudine
AU - Stearns, Vered
AU - Hayes, Daniel F.
N1 - Funding Information:
From the Breast Cancer Program, Lombardi Cancer Center, Georgetown Unicersity, Washington, DC. Supported by American Cancer Society Grant No. CRTG-99-250-OJ-CCE and a grant from The Fashion Footwear Association of New York (FFANY) “Shoes-On-Sale”@. Address reprint requests to Ckudine Isaacs, MD, Diwision of Hematology/Medical Oncology, Georgetown University Medical Center, 3800 Reservoir Road, NW, Washington, DC 20007. Copyright 0 2001 by W.B. Saunders Company 0093,7754/OJ/2SOJ-0001$35.00/O doi:JO.J053/sonc.2000.20742
PY - 2001
Y1 - 2001
N2 - Decisions regarding the use of adjuvant therapy for breast cancer are strongly influenced by the risk of disease recurrence and death. These risks are now determined by examining the currently recognized breast cancer prognostic factors including clinical stage, axillary nodal status, tumor size and grade, hormone receptor status, and presence of lymphovascular involvement. Newer factors are being evaluated in an attempt to more precisely define disease-related prognosis. This article provides an overview of issues that need to be considered when analyzing studies of prognostic factors, as well as a review of the currently recognized and the newer candidate prognostic factors.
AB - Decisions regarding the use of adjuvant therapy for breast cancer are strongly influenced by the risk of disease recurrence and death. These risks are now determined by examining the currently recognized breast cancer prognostic factors including clinical stage, axillary nodal status, tumor size and grade, hormone receptor status, and presence of lymphovascular involvement. Newer factors are being evaluated in an attempt to more precisely define disease-related prognosis. This article provides an overview of issues that need to be considered when analyzing studies of prognostic factors, as well as a review of the currently recognized and the newer candidate prognostic factors.
UR - http://www.scopus.com/inward/record.url?scp=0035110932&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035110932&partnerID=8YFLogxK
U2 - 10.1016/S0093-7754(01)90045-4
DO - 10.1016/S0093-7754(01)90045-4
M3 - Article
C2 - 11254867
AN - SCOPUS:0035110932
SN - 0093-7754
VL - 28
SP - 53
EP - 67
JO - Seminars in oncology
JF - Seminars in oncology
IS - 1
ER -