New perch for the winged helix

Cynthia Wolberger, Robert Campbell

Research output: Contribution to journalShort surveypeer-review

17 Scopus citations


The human transcription factor, RFX1, is found to belong to the winged- helix family of DNA binding proteins, despite an absence of significant sequence similarity. Even more surprising is the very different mode of DNA binding as compared with previously characterized winged-helix proteins that bind to B-form DNA.

Original languageEnglish (US)
Pages (from-to)261-262
Number of pages2
JournalNature Structural Biology
Issue number4
StatePublished - Apr 2000

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry
  • Genetics


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