New light on the integrin switch

Daniel J. Leahy

doi:10.1016/S0969-2126(02)00834-1

New light on the integrin switch

Daniel J. Leahy

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Recent structures of the integrin ectodomain and the cytoplasmic tail complex suggest a model for both "inside-out" and "outside-in" integrin signalling, whereby ligand binding and unclasping the cytoplasmic tails can shift integrin to a high-affinity form.

Original language	English (US)
Pages (from-to)	1152-1154
Number of pages	3
Journal	Structure
Volume	10
Issue number	9
DOIs	https://doi.org/10.1016/S0969-2126(02)00834-1
State	Published - Sep 2002
Externally published	Yes

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1016/S0969-2126(02)00834-1

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year = "2002",

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AU - Leahy, Daniel J.

PY - 2002/9

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AB - Recent structures of the integrin ectodomain and the cytoplasmic tail complex suggest a model for both "inside-out" and "outside-in" integrin signalling, whereby ligand binding and unclasping the cytoplasmic tails can shift integrin to a high-affinity form.

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DO - 10.1016/S0969-2126(02)00834-1

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JO - Structure

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New light on the integrin switch

Abstract

ASJC Scopus subject areas

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