TY - JOUR
T1 - New goals for the U.S. Human Genome Project
T2 - 1998-2003
AU - Collins, Francis S.
AU - Patrinos, Ari
AU - Jordan, Elke
AU - Chakravarti, Aravinda
AU - Gesteland, Raymond
AU - Walters, Le Roy
PY - 1998/10/23
Y1 - 1998/10/23
N2 - The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-98. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, 2 years ahead of previous projections. In the course of completing the sequence, a 'working draft' of the human sequence will be produced by the end of 2001. The plan also includes goals for sequencing technology development; for studying human genome sequence variation; for developing technology for functional genomics; for completing the sequence of Caenorhabditis elegans and Drosophila melanogaster and starting the mouse genome; for studying the ethical, legal, and social implications of genome research; for bioinformatics and computational studies; and for training of genome scientists.
AB - The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-98. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, 2 years ahead of previous projections. In the course of completing the sequence, a 'working draft' of the human sequence will be produced by the end of 2001. The plan also includes goals for sequencing technology development; for studying human genome sequence variation; for developing technology for functional genomics; for completing the sequence of Caenorhabditis elegans and Drosophila melanogaster and starting the mouse genome; for studying the ethical, legal, and social implications of genome research; for bioinformatics and computational studies; and for training of genome scientists.
UR - http://www.scopus.com/inward/record.url?scp=0032561249&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032561249&partnerID=8YFLogxK
U2 - 10.1126/science.282.5389.682
DO - 10.1126/science.282.5389.682
M3 - Review article
C2 - 9784121
AN - SCOPUS:0032561249
SN - 0036-8075
VL - 282
SP - 682
EP - 689
JO - Science
JF - Science
IS - 5389
ER -