New drugs for treating small cell lung cancer

David S. Ettinger

doi:10.1016/S0169-5002(10)80018-2

New drugs for treating small cell lung cancer

David S. Ettinger

School of Medicine

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Recently there has been a number of new active drugs which have been identified for treating patients with SCLC. These drugs include paclitaxel, docetaxel, CPT-11, topotecan and gemcitabine. The range of response rates are as follows for each of the drugs given: (1) to previously untreated patients: paclitaxel (34–41%), topotecan (39%) and gemcitabine (30%), and (2) to previously treated patients: docetaxel (28%), CPT-11 (47%) and topotecan (35%). Further studies with these new drugs utilized in combination chemo therapeutic regimens are needed to define the role of these agents in the treatment of patients with SCLC.

Original language	English (US)
Pages (from-to)	S53-S61
Journal	Lung Cancer
Volume	12
DOIs	https://doi.org/10.1016/S0169-5002(10)80018-2
State	Published - 1995

Keywords

CPT-11
Chemotherapy
Docetaxel
Gemcitabine
Paclitaxel
Small cell lung cancer
Topotecan

ASJC Scopus subject areas

Oncology
Pulmonary and Respiratory Medicine
Cancer Research

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10.1016/S0169-5002(10)80018-2

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title = "New drugs for treating small cell lung cancer",

abstract = "Recently there has been a number of new active drugs which have been identified for treating patients with SCLC. These drugs include paclitaxel, docetaxel, CPT-11, topotecan and gemcitabine. The range of response rates are as follows for each of the drugs given: (1) to previously untreated patients: paclitaxel (34–41%), topotecan (39%) and gemcitabine (30%), and (2) to previously treated patients: docetaxel (28%), CPT-11 (47%) and topotecan (35%). Further studies with these new drugs utilized in combination chemo therapeutic regimens are needed to define the role of these agents in the treatment of patients with SCLC.",

keywords = "CPT-11, Chemotherapy, Docetaxel, Gemcitabine, Paclitaxel, Small cell lung cancer, Topotecan",

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year = "1995",

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T1 - New drugs for treating small cell lung cancer

AU - Ettinger, David S.

PY - 1995

Y1 - 1995

N2 - Recently there has been a number of new active drugs which have been identified for treating patients with SCLC. These drugs include paclitaxel, docetaxel, CPT-11, topotecan and gemcitabine. The range of response rates are as follows for each of the drugs given: (1) to previously untreated patients: paclitaxel (34–41%), topotecan (39%) and gemcitabine (30%), and (2) to previously treated patients: docetaxel (28%), CPT-11 (47%) and topotecan (35%). Further studies with these new drugs utilized in combination chemo therapeutic regimens are needed to define the role of these agents in the treatment of patients with SCLC.

AB - Recently there has been a number of new active drugs which have been identified for treating patients with SCLC. These drugs include paclitaxel, docetaxel, CPT-11, topotecan and gemcitabine. The range of response rates are as follows for each of the drugs given: (1) to previously untreated patients: paclitaxel (34–41%), topotecan (39%) and gemcitabine (30%), and (2) to previously treated patients: docetaxel (28%), CPT-11 (47%) and topotecan (35%). Further studies with these new drugs utilized in combination chemo therapeutic regimens are needed to define the role of these agents in the treatment of patients with SCLC.

KW - CPT-11

KW - Chemotherapy

KW - Docetaxel

KW - Gemcitabine

KW - Paclitaxel

KW - Small cell lung cancer

KW - Topotecan

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U2 - 10.1016/S0169-5002(10)80018-2

DO - 10.1016/S0169-5002(10)80018-2

M3 - Article

C2 - 7551957

AN - SCOPUS:0029006581

SN - 0169-5002

VL - 12

SP - S53-S61

JO - Lung Cancer

JF - Lung Cancer

ER -

New drugs for treating small cell lung cancer

Abstract

Keywords

ASJC Scopus subject areas

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