New delivery systems for brain tumor therapy

E. P. Sipos; H. Brem

doi:10.1016/s0733-8619(18)30019-7

New delivery systems for brain tumor therapy

E. P. Sipos, H. Brem

School of Medicine

Research output: Contribution to journal › Review article › peer-review

24 Scopus citations

Abstract

Therapy of brain tumors has been limited by lack of effective methods of drug delivery. Systemic administration often fails to achieve therapeutic concentrations of drugs within intracranial tumors despite toxic systemic levels. This article discusses new methods for delivering therapeutic agents to brain tumors, including intra-arterial, intrathecal, intraventricular, and interstitial administration techniques.

Original language	English (US)
Pages (from-to)	813-825
Number of pages	13
Journal	Neurologic clinics
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/s0733-8619(18)30019-7
State	Published - 1995

ASJC Scopus subject areas

Clinical Neurology

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10.1016/s0733-8619(18)30019-7

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title = "New delivery systems for brain tumor therapy",

abstract = "Therapy of brain tumors has been limited by lack of effective methods of drug delivery. Systemic administration often fails to achieve therapeutic concentrations of drugs within intracranial tumors despite toxic systemic levels. This article discusses new methods for delivering therapeutic agents to brain tumors, including intra-arterial, intrathecal, intraventricular, and interstitial administration techniques.",

author = "Sipos, {E. P.} and H. Brem",

year = "1995",

doi = "10.1016/s0733-8619(18)30019-7",

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T1 - New delivery systems for brain tumor therapy

AU - Sipos, E. P.

AU - Brem, H.

PY - 1995

Y1 - 1995

N2 - Therapy of brain tumors has been limited by lack of effective methods of drug delivery. Systemic administration often fails to achieve therapeutic concentrations of drugs within intracranial tumors despite toxic systemic levels. This article discusses new methods for delivering therapeutic agents to brain tumors, including intra-arterial, intrathecal, intraventricular, and interstitial administration techniques.

AB - Therapy of brain tumors has been limited by lack of effective methods of drug delivery. Systemic administration often fails to achieve therapeutic concentrations of drugs within intracranial tumors despite toxic systemic levels. This article discusses new methods for delivering therapeutic agents to brain tumors, including intra-arterial, intrathecal, intraventricular, and interstitial administration techniques.

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U2 - 10.1016/s0733-8619(18)30019-7

DO - 10.1016/s0733-8619(18)30019-7

M3 - Review article

C2 - 8583998

AN - SCOPUS:0028792172

SN - 0733-8619

VL - 13

SP - 813

EP - 825

JO - Neurologic clinics

JF - Neurologic clinics

IS - 4

ER -

New delivery systems for brain tumor therapy

Abstract

ASJC Scopus subject areas

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