The chromophores generally mentioned in evaluating the physical interactions of laser radiation with tissue are: melanin, xanthrophyl, water, the corneal and lenticular proteins, hemoglobin and oxygenated hemoglobin. However, other natural chromophores exist and should not be neglected. For example, in studies of retinal thermal injury at wavelengths in the 600-1064 nm region, it has become clear that other chromophores must play a role. The potential for finding other useful target chromophores for retinal photocoagulation and for refractive surgery will be considered. Collagen is one target molecule of particular interest. Multiphoton absorption may be of potential use. Exogenous chromophores targeted to certain structures may also offer promise.
|Number of pages
|Lasers and Light in Ophthalmology
|Published - 1988
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