Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease

Keyphrases

• Neutrophils 100%
• Epithelial Barrier 100%
• Airway Disease 100%
• Oncostatin M 100%
• Nasal Polyps 33%
• Granulocyte Colony-stimulating Factor (G-CSF) 16%
• Chronic Rhinosinusitis 16%
• Severe Asthma 16%
• M-level 16%
• Control Subjects 11%
• Asthma Symptoms 11%
• Hematopoietic Cells 11%
• Blood Samples 11%
• Neutrophil Elastase 11%
• Flow Cytometry Analysis 11%
• Biopsy Specimen 5%
• T Cells 5%
• Protein Level 5%
• Eosinophils 5%
• Colocalization 5%
• Physiologic Levels 5%
• Whole Blood 5%
• Control Tissue 5%
• Cell-to-cell 5%
• B Cells 5%
• Living Cells 5%
• Inducer 5%
• Airway Epithelium 5%
• Macrophages 5%
• M Protein 5%
• Specific Antibodies 5%
• Paraffin Embedding 5%
• Bronchoalveolar Lavage Fluid 5%
• Supernatant 5%
• Barrier Function 5%
• Induced Sputum 5%
• CD45+ Cells 5%
• CD45+ 5%
• Transbronchial Biopsy 5%
• Fluorescent Labeling 5%
• Resident Cells 5%
• M Cells 5%
• CD14+CD16+ 5%
• Siglec-8 5%
• CSF Levels 5%
• Segmental Allergen Challenge 5%
• Peripheral Blood Neutrophils 5%
• Arginase-1 (Arg-1) 5%
• Follistatin-like 1 5%
• Cell Markers 5%
• Moderate-to-severe Asthma 5%

Immunology and Microbiology

• Cytokine 100%
• Neutrophil 100%
• Oncostatin M 100%
• Airway 100%
• Granulocyte Macrophage Colony-Stimulating Factor 16%
• Severe Asthma 16%
• In Vitro 11%
• Lineages 5%
• T Cell 5%
• B Cell 5%
• Macrophage 5%
• Staining 5%
• Sputum 5%
• Asthma 5%
• Allergen 5%
• Supernatant 5%
• Eosinophil 5%
• Bronchoalveolar Lavage Fluid 5%
• Hematopoietic Cell 5%
• CD16 5%
• Sialic Acid Binding Immunoglobulin Like Lectin 5%
• Epithelium 5%