Abstract
PURPOSE OF REVIEW: This article provides an update on the evaluation and treatment of neurosarcoidosis. RECENT FINDINGS: The broad range of clinical manifestations of neurosarcoidosis has recently expanded to include painful small fiber neuropathy. Although definitive diagnosis remains a challenge, fluorodeoxyglucose positron emission tomographic (FDG-PET) scan and high-resolution CT allow for improved detection of systemic sarcoidosis. In addition, endobronchial ultrasound-guided transbronchial needle aspiration provides a less invasive means of tissue confirmation of systemic sarcoidosis than mediastinoscopy. Although not standardized, treatment strategies for neurosarcoidosis now commonly include tumor necrosis factor-α antagonists in combination with corticosteroids and other cytotoxic agents for patients with severe disease. SUMMARY: Advances in the diagnosis and management of neurosarcoidosis may benefit the patient and clinician faced with this multifaceted disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 545-559 |
| Number of pages | 15 |
| Journal | CONTINUUM Lifelong Learning in Neurology |
| Volume | 20 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 2014 |
| Externally published | Yes |
ASJC Scopus subject areas
- Clinical Neurology
- Genetics(clinical)