Abstract
The primary purpose of the heart is to contract and pump blood to the entire body and all peripheral organs. Heart rate and cardiac output are tightly regulated so the heart can adjust to meet the needs of the organism under any given circumstance. This regulation is provided by the autonomic nervous system, including hormones and other secreted factors. In this chapter, we discuss the physiological mechanisms by which cardiac function is controlled and modulated by the autonomic (sympathetic & parasympathetic) nervous system, by the endocrine organs (mainly pituitary and adrenal glands), and, finally, by its own intrinsic endocrine system (cardiac hormones). Particular emphasis is given to molecular receptor signaling mechanisms underlying these processes.
Original language | English (US) |
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Title of host publication | Endocrinology of the Heart in Health and Disease |
Subtitle of host publication | Integrated, Cellular, and Molecular Endocrinology of the Heart |
Publisher | Elsevier Inc. |
Pages | 207-227 |
Number of pages | 21 |
ISBN (Electronic) | 9780128031124 |
ISBN (Print) | 9780128031117 |
DOIs | |
State | Published - 2017 |
Keywords
- Adrenal gland
- Aldosterone
- Angiotensin
- Autonomic nervous system
- Cardiac function
- Catecholamines
- Neuronal hormones
- Parasympathetic
- Signal transduction
- Sympathetic
ASJC Scopus subject areas
- Medicine(all)