Neuronal and glial cytoskeletons

Don W. Cleveland, Paul N. Hoffman

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Long-awaited evidence for in vivo functions of the major neuronal microtubule associated proteins indicates that they are directly involved in neurite extension. Companion evidence reveals an intrinsic role for glial intermediate filaments in glial cell extension along neurites and for neurofilaments in establishing axonal caliber. New fluorescence and photoactivation experiments require a re-thinking of models of slow axonal transport and of the part the cytoskeleton plays in axonal guidance.

Original languageEnglish (US)
Pages (from-to)346-353
Number of pages8
JournalCurrent Opinion in Neurobiology
Issue number3
StatePublished - Oct 1991
Externally publishedYes

ASJC Scopus subject areas

  • General Neuroscience


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