Neuroepithelioma (neuroblastoma) arising in an adult - A case report

Cytogenetic studies on neuroblastomas arising in children have revealed consistent abnormalitics of the short arm of chromosome number 1. Partly because of the rare occurence of neuroblastomas in adults, extensive cytogenetic studies in this group of patients have not been performed. We report a case of a neuroepithelioma (neuroblastoma) arising in a 50-year-old male patient. On chromosome analysis of a metastasis, a stemline with karyotype 47,XY, +der1(1 qter... 1 cen::1q21...1 qter) was identified. The possible consequences of this result and those of results previously reported in the literature are discussed.