Neuroendocrine carcinoma of the oral cavity.

T. L. Benning, R. T. Vollmer, B. J. Crain, J. D. Shelburne

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


We report the clinical and pathologic features of a small cell neuroendocrine carcinoma arising in the oral cavity of a 63-year-old man. The tumor stained positively with neuron-specific enolase and had dense core granules ultrastructurally. Chemotherapy ordinarily given for pulmonary small cell carcinoma induced a clinical remission. When the tumor recurred 8 mo later, focal squamous differentiation was present within the neuroendocrine carcinoma. The patient died 2.5 yr after presentation.

Original languageEnglish (US)
Pages (from-to)631-634
Number of pages4
JournalModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Issue number5
StatePublished - Sep 1990
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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